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| Pathologic Feature | Crohn's disease | Intestinal tuberculosis | BJD (Bovine Johne's Disease) | Other mycobacterioses (in humans) |
|---|---|---|---|---|
| Segmental distribution | Yes | Yes | Yes | Leprosy |
| Strictures | Yes | Yes | No | NKa |
| Obstruction | Yes | Yes | No | NK |
| Skin lesions | Yes | Yes | Yes | Leprosy |
| Perforations | Yes | Yes | NK | NK |
| Stenosis | Yes | Yes | Yes | NK |
| Abdominal mass | Yes | Yes | No | NK |
| Fibrosis | Yes | Yes | No | NK |
| Ulcerations | Yes | Yes | Yes | Leprosy |
| Transmural inflammation | Yes | Yes | Yes | NK |
| Abdominal edema | Yes | No | NK | NK |
| Fissures | Yes | Yes | No | NK |
| Fistulae - Internal | Yes | Yes | No | Various |
| Fistulae - External | Yes | Yes | No | Various |
| Sinus tracts | Yes | Yes | No | NK |
| Lymphoid hyperplasia | Yes | Yes | Yes | Leprosy |
| Pseudopolyps | Yes | Yes | No | NK |
| Granulomas | Yes | Yes | Yes | All |
| Noncaseating granulomas | Yes | Yes(25%) | Yes | Various |
| Nonspecific inflammation | Yes | Yes | Yes | Various |
| Giant cells - Foreign body | Yes | Yes | Yes | NK |
| Giant cells - Langhans | Yes | Yes | Yes | All |
a NK. Not Known or not applicable due to site specificity.
Source: "Crohn's Disease and the Mycobacterioses: A Review and Comparison of Two Disease Entities", by Rodrick Chiodini, January 1989.
Source: http://archive.crohn.ie/pathsims.htm
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