Mycobacterium Paratuberculosis in Animals.

Paratuberculosis in animals has been the subject of an enormous amount of study by the veterinary world. To see the extent of this research, access the MEDLINE database (available free from MedScape) and search on the keywords "animal and paratuberculosis". In many animals, M. paratuberculosis causes a chronic granulomatous enteritis, which is extremely similar to Crohn's Disease in its pathology. Below, I have listed a selection of studies which describe paratuberculosis in various animals.

A far more comprehensive list of the animals which can be infected by Mycobacterium paratuberculosis is available in the paper Ruminant Paratuberculosis (Johne's disease):- The current status and future prospects

• Cattle. Economically, BJD (Bovine Johne's Disease), is one of the beef and dairy industries greatest problems. The disease is difficult to recognise, difficult to control and uneconomical to treat. Rather than list the multitude of veterinary research papers on BJD, I instead refer you to the "Johnes Disease Information Center."

• Alpaca. Here is a study from Australia that describes paratuberculosis in alpacas. "Johne's disease in alpacas (Lama pacos) in Australia".

• Antelope. "Paratuberculosis in saiga antelope (Saiga tatarica) and experimental transmission to domestic sheep."

• Ass. "Probable paratuberculosis in a Sicilian ass."

• Chicken. This study fulfills Kochs Postulate for Crohn's Disease, by taking an organism isolated from a Crohn's Patient, and using it to induce disease in chickens. This proves that Crohn's Disease is an infectious disease. "Experimental disease in young chickens induced by a Mycobacterium paratuberculosis isolate from a patient with Crohn's disease."

• Dog. Unfortunately, there is no abstract with this paper since it was originally written in German, but I have included the reference for completeness. "[Paratuberculosis in a dog]"

• Elk.Unfortunately, there is no abstract with this paper, but I have included the reference for completeness. "Paratuberculosis in tule elk in California."

• Gerbil. "Susceptibility of the Mongolian gerbil (Meriones unguiculatus) to Mycobacterium paratuberculosis."

• Goat. "Paratuberculosis in a large goat herd."

• Horse. Unfortunately, there is no abstract with this paper, but I have included the reference for completeness. "Susceptibility of horses to Mycobacterium paratuberculosis."

• Macaque. Here is reference that describes paratuberculosis in stump-tailed macaques, a sub-human primate. "Mycobacterium paratuberculosis infection in a colony of stumptail macaques (Macaca arctoides)."

• Rabbit. Here is a few studies with rabbits.
  • "Granulomatous enteritis following oral inoculation of newborn rabbits with Mycobacterium paratuberculosis of bovine origin."

  • "A rabbit model for study of Mycobacterium paratuberculosis infection."

  • "Intestinal lesions resembling paratuberculosis in a wild rabbit (Oryctolagus cuniculus)"

• Red deer. "Paratuberculosis in farmed red deer (Cervus elaphus) in Ireland."

• Sheep. "Description and classification of different types of lesion associated with natural paratuberculosis infection in sheep."

• White tailed deer. "Presumptive paratuberculosis in a Virginia white-tailed deer."

Source: http://archive.crohn.ie/animal.htm
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