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| Title: Incidence of Crohn's disease in four counties in southeastern Norway, 1990-93. A prospective population-based study. The Inflammatory Bowel South-Eastern Norway (IBSEN) Study Group of Gastroenterologists. | ||||
| Title Abreviation: Scand J Gastroenterol | Date of Pub: 1996 Apr | |||
| Author: Moum B; Vatn MH; Ekbom A; Aadland E; Fausa O; Lygren I; Stray N; Sauar J; Schulz T; | ||||
| Issue/Part/Supplement: 4 | Volume Issue: 31 | Pagination: 355-61 | ||
| MESH Headings: Adolescence*; Adult*; Aged*; Crohn Disease*; Female; Human; Intestine, Large*; Intestine, Small*; Male; Middle Age*; Norway; Prospective Studies*; Support, Non-U.S. Gov't; -PG-; | ||||
| Journal Title Code: UCS | Publication Type: JOURNAL ARTICLE | |||
| Date of Entry: 960923N | Entry Month: 9611 | |||
| Country: NORWAY | Index Priority: 2 | |||
| Language: Eng | Unique Identifier: 96293626 | |||
| Unique Identifier: 96293626 | ISSN: 0036-5521 | |||
| Abstract: BACKGROUND: Standardized criteria for Crohn's disease (CD) have only recently been developed, and prospective community-based incidence studies have been performed only during the past 3 decades. Geographic variations in incidence may therefore be due to differences in study design. METHODS: From 1 January 1990 to 31 December 1993 all new cases of CD in four counties in southeastern Norway were prospectively registered. RESULTS: A total of 225 new cases yielded an annual incidence of 5.8/10(5), with the highest incidence in mixed rural-urban areas. A peak of 11.2/10(5) in the annual incidence was found for the age group 15 to 24 years, with no significant differences in the overall annual incidence by gender. An average duration of 6 months of disease before diagnosis was unchanged during the 4 years. About half of the patients had isolated colonic disease, and one-quarter had isolated small-bowel disease. CONCLUSIONS: This study confirms the high incidence figures for Scandinavia, with a particularly high incidence in mixed rural-urban areas. Ileocolonoscopy improves the accuracy of the diagnosis and of the determination of disease extent, which may have therapeutic implications for the treatment and follow-up of patients. | ||||
| Abstract By: Author | ||||
| Address: Dept. of Internal Medicine, Ostfold Central Hospital, Fredrikstad, Sweden. | ||||