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Title: Epidemiological characteristics of inflammatory bowel disease in Bologna, Italy--incidence and risk factors.
Title Abreviation: Digestion Date of Pub: 1993
Author: Tragnone A; Hanau C; Bazzocchi G; Lanfranchi GA;
Issue/Part/Supplement: 3 Volume Issue: 54 Pagination: 183-8
MESH Headings: Adolescence; Adult; Aged; Child; Colitis, Ulcerative (*EP); Crohn Disease (*EP); Female; Human; Incidence; Italy (EP); Male; Middle Age; Prospective Studies; Risk Factors; Sex Factors; Smoking (EP); Support, Non-U.S. Gov't; -AA-;
Journal Title Code: E9A Publication Type: JOURNAL ARTICLE
Date of Entry: 930930NEntry Month: 9312
Country: SWITZERLAND Index Priority: 2
Language: Eng Unique Identifier: 93365984
Unique Identifier: 93365984 ISSN: 0012-2823
Abstract: Recently, in Bologna, an inflammatory bowel disease incidence of 7.7/10(5)/year has been calculated, about one third of that reported in Northern Europe, confirming the existence of a 'North-South gradient'. A first peak of incidence was observed at 20-29 years of age and a second peak at 60-69 years of age for ulcerative colitis (UC) alone. A prevalence of UC males, mainly after the 7th decade, and of Crohn's disease (CD) females in the first peak was found. A greater frequency of ex-smokers in UC, with a relative risk (RR) significantly higher in males for all age groups (RR = 6.1; p < 0.01) and of smokers in CD with a RR significantly higher in 20- to 29-year-old females (RR = 11.6; p < 0.05) was observed. A different pattern for the two diseases exists: male ex-smokers and young female smokers are at risk of developing UC and CD, respectively.
Abstract By: Author
Address: Cattedra di Medicina Interna, University of Bologna, Italy.