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Title: Prevalence of Crohn's disease and simultaneous occurrence of extraintestinal complications and cancer. An epidemiologic study in adults.
Title Abreviation: Scand J Gastroenterol Date of Pub: 1996 Jan
Author: Lindgren A; Wallerstedt S; Olsson R;
Issue/Part/Supplement: 1 Volume Issue: 31 Pagination: 74-8
MESH Headings: Adolescence; Adult; Aged; Aged, 80 and over; Child; Cholangitis, Sclerosing (*EP); Crohn Disease (*EP); Eye Diseases (EP); Female; Human; Intestinal Fistula (*EP); Intestinal Neoplasms (*EP); Joint Diseases (EP); Male; Middle Age; Neoplasms (*EP); Population Surveillance; Prevalence; Skin Diseases (EP); Sweden (EP); -AA-;
Journal Title Code: UCS Publication Type: JOURNAL ARTICLE
Date of Entry: 961025NEntry Month: 9701
Country: NORWAY Index Priority: 2
Language: Eng Unique Identifier: 96402874
Unique Identifier: 96402874 ISSN: 0036-5521
Abstract: BACKGROUND: Very dissimilar prevalence figures for Crohn's disease (CD) have been reported from different regions of Scandinavia. There are few reports on the occurrence of liver, joint, skin, and eye disease and gastrointestinal cancer in CD. METHODS: All patients > or = 16 years old with CD living in a well-defined catchment area on 1 March 1990 were identified from the previous 10 years' registers of inpatients and outpatients. The records were screened for evidence of extraintestinal complications and fistulas. RESULTS: The prevalence of CD was 94/10(5) (95% confidence interval, 84-104) inhabitants > or = 16 years old. Signs of liver disease were encountered in 1 of 10 patients, and other extraintestinal complications and intestinal cancer occurred in 1-3%. The true prevalence of primary sclerosing cholangitis could not be assessed. CONCLUSION: The prevalence of CD was midway between recent figures from Orebro and Copenhagen. Fistulas and pathologic liver laboratory test results were more prevalent when CD involved both the large and small bowel.
Abstract By: Author
Address: Dept. of Internal Medicine, Sahlgrenska Hospital, Sweden.