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Title: Mycobacterium tuberculosis infection in the acquired immunodeficiency syndrome. A review of 14 patients.
Title Abreviation: Tubercle Date of Pub: 1986 Dec
Author: Duncanson FP; Hewlett D Jr; Maayan S; Estepan H; Perla EN; McLean T; Rodriguez A; Miller SN; Lenox T; Wormser GP;
Issue/Part/Supplement: 4 Volume Issue: 67 Pagination: 295-302
MESH Headings: Acquired Immunodeficiency Syndrome (*CO); Adult; Antitubercular Agents (TU); Follow-Up Studies; Homosexuality; Human; Male; Middle Age; New York City; Substance Abuse; Time Factors; Tuberculosis (*CO); Tuberculosis, Pulmonary (CO/DT); -RN-;
Journal Title Code: WH9 Publication Type: JOURNAL ARTICLE
Date of Entry: 871103NEntry Month: 8801
Country: SCOTLAND Index Priority: 2
Language: Eng Unique Identifier: 88018932
Unique Identifier: 88018932 ISSN: 0041-3879
Abstract: The clinical findings in 13 drug abusers and one homosexual man with tuberculosis and the acquired immunodeficiency syndrome (AIDS) from New York City are described. Tuberculosis preceded the diagnosis of AIDS in nine of the 14 patients by a mean of 7 months and occurred within the same month in the remaining five. The presence of thrush, generalised lymphadenopathy, lymphopenia, cutaneous anergy and chest radiographs showing hilar adenopathy and/or lower lobe infiltrates was common among the patients in whom tuberculosis preceded AIDS. Eight of our patients had extra-pulmonary tuberculosis, six had disseminated tuberculosis and five had tuberculous lymphadenitis. Cultures of tissue biopsies may be positive for Mycobacterium tuberculosis despite the absence of acid fast bacilli or granulomas on microscopic examination. Tuberculosis generally responded to chemotherapy, but the majority of patients died from opportunist infections.
Abstract By: Author
Address: Department of Medicine of Lincoln Hospital, New York City, New York.