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Title: Intestinal tuberculosis, Crohn's disease and ulcerative colitis in an urban black population.
Title Abreviation: S Afr Med J Date of Pub: 1984 Jan 14
Author: Segal I;
Issue/Part/Supplement: 2 Volume Issue: 65 Pagination: 37-44
MESH Headings: Adult; Blacks; Colitis, Ulcerative (*EP); Crohn Disease (*EP); Female; Human; Male; Middle Age; South Africa; Tuberculosis, Gastrointestinal (*EP); Urban Population; -AA-;
Journal Title Code: U4R Publication Type: JOURNAL ARTICLE
Date of Entry: 840227NEntry Month: 8405
Country: SOUTH AFRICA Index Priority: 1
Language: Eng Unique Identifier: 84121688
Unique Identifier: 84121688 ISSN: 0038-2469
Abstract: The clinical, epidemiological and pathological manifestations of intestinal tuberculosis, Crohn's disease and ulcerative colitis in the Johannesburg Black population are reviewed. Crohn's disease and particularly ulcerative colitis have emerged as definite disease entities in urban Blacks. There is an evident similarity between the clinical manifestations of intestinal tuberculosis and of Crohn's disease, and also between those of Crohn's disease and ulcerative colitis. Furthermore the data suggest that genetic and environmental factors play a vital role in susceptibility to these diseases. The similarity between the clinicopathological manifestations of intestinal tuberculosis and those of Crohn's disease lends support to the view that microbial, viral or cellular toxic agents are involved in the aetiology of Crohn's disease. Moreover, the clinical and epidemiological features of ulcerative colitis support the concept that environmental factors present in an urbanized milieu are important in its aetiology.
Abstract By: Author